Mutagenic Effects of Iron Oxide Nanoparticles on Biological Cells

In recent years, there has been an increased interest in the design and use of iron oxide materials with nanoscale dimensions for magnetic, catalytic, biomedical, and electronic applications. The increased manufacture and use of iron oxide nanoparticles (IONPs) in consumer products as well as industrial processes is expected to lead to the unintentional release of IONPs into the environment. The impact of IONPs on the environment and on biological species is not well understood but remains a concern due to the increased chemical reactivity of nanoparticles relative to their bulk counterparts. This review article describes the impact of IONPs on cellular genetic components. The mutagenic impact of IONPs may damage an organism’s ability to develop or reproduce. To date, there has been experimental evidence of IONPs having mutagenic interactions on human cell lines including lymphoblastoids, fibroblasts, microvascular endothelial cells, bone marrow cells, lung epithelial cells, alveolar type II like epithelial cells, bronchial fibroblasts, skin epithelial cells, hepatocytes, cerebral endothelial cells, fibrosarcoma cells, breast carcinoma cells, lung carcinoma cells, and cervix carcinoma cells. Other cell lines including the Chinese hamster ovary cells, mouse fibroblast cells, murine fibroblast cells, Mytilus galloprovincialis sperm cells, mice lung cells, murine alveolar macrophages, mice hepatic and renal tissue cells, and vero cells have also shown mutagenic effects upon exposure to IONPs. We further show the influence of IONPs on microorganisms in the presence and absence of dissolved organic carbon. The results shed light on the transformations IONPs undergo in the environment and the nature of the potential mutagenic impact on biological cells.     

Stochastic analysis of strongly non-linear elastic impact system with Coulomb friction excited by white noise

The stochastic response of frictionally damped strongly non-linear elastic impact oscillator subjected to white noise excitation and its stochastic bifurcation are considered. By the stochastic averaging method based on generalized harmonic function, one can obtain the stationary probability density function of this system. The effects of system parameters on the responses are investigated and the analytical results were verified by comparing with numerical results from Monte Carlo simulations. Stochastic bifurcations are discussed through a qualitative change of the stationary probability distribution, which indicates that the coefficient of friction, damping constant of the elastic impact force respectively, can be treated as bifurcation parameters.     

Variation in the effect of system usage and individual impact: A meta-regression of empirical findings

The relationship between system usage and individual impact has received considerable attention in prior studies. However, the results for the relationship have been mixed. This study hypothesizes that the variation in the effect of system usage on individual impact may be attributed to characteristics of the research contexts. This research examines the effects of voluntariness of use, number of organizations, number of respondents, type of respondents, and information system type, while controlling for geographic region and industry sector using meta-regression methods to examine the findings from 74 studies published between 1992 and 2018. Implications for research and practice are discussed.     

煤层顶板硬岩大直径定向钻孔施工关键技术

根据顶板高位定向钻孔快速钻进成孔与工作面卸压瓦斯高效抽采治理需要，针对现有螺杆马达定向钻进技术与分级扩孔方法存在的问题，开展了顶板硬岩定向钻进与大直径扩孔钻进关键技术研究，开发了冲击回转定向钻进技术、扭冲回转定向钻进技术、扭冲旋转扩孔技术以及双级双速扩孔技术等钻孔提速新技术，研制了冲击螺杆马达、矿用小直径扭力冲击器、双级双速螺杆马达、组合式扩孔钻头等配套钻具。综合试验结果表明，硬岩定向钻孔平均机械钻进效率达到8.34 m/h，最高达到13.6 m/h，较常规螺杆马达定向钻进技术提升20%~30%；硬岩大直径扩孔终孔直径达到200 mm，机械钻进效率平均达到5.6 m/h以上，最高达到10.5 m/h。该技术提升了顶板硬岩定向钻进效率与大直径扩孔钻进效率，缩短了顶板高位定向钻孔的综合施工周期，为大直径高位定向长钻孔快速成孔与高效抽采治理回采工作面卸压瓦斯提供了可靠的技术手段。     

焊接线能量对高强钢焊接接头组织性能的影响

采用1.3、1.6、1.9 kJ/mm 3种不同线能量对960QT钢进行焊接，研究了线能量对960QT钢焊接接头组织和性能的影响。研究表明，随着线能量的增加，焊接接头强度下降，但塑性提高，焊缝冲击韧性变化不大，热影响区冲击韧性先降低后增大，热影响区冲击韧性均高于焊缝。对3种线能量下960QT高强钢的焊接接头进行金相分析，发现焊缝组织主要为针状铁素体和粒状贝氏体。随着线能量的增加，针状铁素体发生粗化，数量相对减少，粒状贝氏体数量增多。焊接接头热影响区的金相组织主要为板条M/B和粒状贝氏体。随着焊接线能量的增大，冷却速率减小，粒状贝氏体组织数量相对增加，而板条贝氏体组织的数量逐渐减少。     

低速冲击下的界面响应和磨损行为*

为探究低速冲击下界面响应与磨损行为之间的联系，开展多周次的低速冲击磨损实验；通过分析冲击过程中的接触力峰值、接触时长、接触力冲量、动能耗散等，研究冲击速度对接触界面的力学响应的影响；通过对冲击磨痕的磨损轮廓和形貌、磨损体积的检测分析，以及对磨痕区域元素组分变化的测试，研究冲击速度对接触界面磨损损伤行为的影响。结果表明：冲击速度的增加会导致接触界面在更短的时间内受到更强烈的力学作用；能量吸收率对冲击速度的变化不敏感，但冲击速度的提高会导致单位能量造成的磨损损伤逐渐降低；冲击磨痕可分为以塑性变形和以剥层磨损为主要损伤形式的2种区域；磨损区内经历了严重的摩擦氧化，并随着冲击速度的增加发生冲击副材料转移。因此，冲击速度越高，接触界面间的摩擦越剧烈，形成的表面氧化层避免了冲击副与基底材料的直接接触，延缓了磨损损伤的进一步发展。     

辐照用小尺寸样品力学性能表征技术研究进展

由于辐照空间尺寸限制、降低样品放射性和提高辐照参数精度等原因，小尺寸样品被广泛应用于核反应堆材料的辐照后力学性能表征。本文就国内外小尺寸拉伸、冲击、断裂韧性、疲劳、蠕变和小冲杆等测试表征技术的研究现状进行了综合论述，分析了小尺寸样品测试中的关键影响因素以及数据归一化方法，总结了小尺寸样品存在的问题，并结合我国需求对小尺寸样品技术的发展进行了分析和展望，以期为小尺寸样品技术及测试分析数据进一步规范化和工程应用发展提供参考。     

水电工程下泄生态基流常用计算方法及软件开发

为了分析及确立生态基流,为水电工程环境影响评价提供依据,针对水电工程生态基流估算及决策过程繁复等问题,以2001—2015年水电工程环境影响评价及相关法律法规为基础,分析我国生态基流管理实践中使用最广泛的4种计算方法,即Tennant法、月基本流量法、最小流量法及7Q10法,并编制生态基流决策支持软件,并应用软件在汉江流域进行实例验证。结果表明,该软件能够提供多种计算方法及对比分析功能,可为水电工程下泄生态基流计算及决策提供计算平台。4种计算方法在汉江流域计算结果差异较大。总体而言,干流适合最小流量法及Tennant法,支流适合Tennant法。研究成果具有较大的实际应用和推广价值。     

锻后热处理对AF1410钢冲击韧性和晶粒度的影响

研究了AF1410钢锻后不同热处理温度和保温时间对冲击韧性和晶粒度的影响。结果表明,随锻后热处理温度的降低,AF1410冲击吸收能量先升高后降低,并且AF1410晶粒度尺寸逐渐减小,但减小幅度变小且趋于均匀化。同一锻后热处理温度下不同保温时间对AF1410冲击韧性有一定的影响,但影响不大,而对晶粒度几乎无影响。